NCT01706341

The Effect of Administering a Small Dose of Glucose During Cesarean Section

The Effect of Administering a Small Dose of Glucose on the Pregnant Women and Their Neonates During Cesarean Section

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Nagoya City University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the effect of administering a small dose of glucose on the pregnant women and their neonates during cesarean section. We investigate the safety and efficacy of use of a glucose-containing solution for the pregnant women and the neonates.

Detailed description

Rapid infusion of large amount of glucose is associated with fetal hyperglycemia, hyperinsulinemia, and neonatal hypoglycemia. However, the effect of small dose of glucose is unclear. We conducted a pilot study of small dose of glucose. We investigated the effect of a glucose-containing fluid on the blood sugar of the umbilical artery. We found that in the case of no-glucose-containing fluid, there were some cases in which umbilical arterial concentration of glucose was less than 50 mg/dl, which might cause neonatal hypoglycemia. In addition, in the case of 1%-glucose-containing fluid, mean umbilical arterial concentration of glucose was 97 mg/dl. The purpose of this study is to investigate the effect of administering a small dose of glucose on the pregnant women and their neonates during cesarean section. We investigate the safety and efficacy of use of a glucose-containing solution for the pregnant women and the neonates.

Conditions

• Cesarean Section

Interventions

Type	Name	Description
DRUG	administer acetate Ringer's solution	During cesarean section under spinal anesthesia, each acetate Ringer's solution is administered before delivery.
DRUG	acetate Ringer's solution containing no glucose
DRUG	acetate Ringer's solution containing 1% glucose

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-10-01
• First posted: 2012-10-15
• Last updated: 2012-10-15

Locations

1 site across 1 country: Japan