NCT01705639

Melatonin and Glucose Tolerance Among Individuals With a Variant of the MTNR1B Gene

Does Melatonin Treatment Affect Glucose Tolerance Among Individuals With a Variant (rs10830963) of the Melatonin Receptor 1B (MTNR1B) Gene?

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 45 (actual)
• Sponsor: University of Helsinki · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The effect of 3 months of melatonin 4mg treatment on glucose tolerance in different variants of the melatonin receptor 1B gene will be evaluated. The following will be done at 0 and 3 months: * OGTT * questionnaires about sleep and activity * Actigraph * Anthropometry * Blood pressure

Detailed description

http://www.sciencedirect.com/science/article/pii/S1550413116301607

Conditions

• Diabetes
• Glucose Tolerance

Interventions

Type	Name	Description
DRUG	Melatonin	All subjects receive the same dose of melatonin

Timeline

• Start date: 2012-11-01
• Primary completion: 2014-08-01
• Completion: 2014-08-01
• First posted: 2012-10-12
• Last updated: 2017-01-04

Locations

2 sites across 1 country: Finland