NCT01705327

Fox Investigation for New Discovery of Biomarkers

Fox Investigation for New Discovery of Biomarkers (BioFIND)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 240 (estimated)
• Sponsor: Michael J. Fox Foundation for Parkinson's Research · Academic / Other
• Sex: All
• Age: 55 Years – 93 Years
• Healthy volunteers: Accepted

Summary

This is an observational, multi-center study to assess clinical features and biologic biomarkers in Parkinson's disease (PD) patients compared to healthy controls (HC). The primary objective of this study is to discover clinical and biologic markers of PD for use in clinical trials of disease-modifying therapies.

Detailed description

BioFIND is a two-year observational clinical study designed to discover and verify biomarkers of Parkinson's disease (PD). BioFIND is collecting clinical data and biospecimens, including blood and cerebrospinal fluid (CSF), in a population of 120 well-defined, moderately advanced PD subjects and 120 healthy controls. BioFIND will follow standardized data acquisition protocols to ensure that tests and assessments conducted at multiple sites can be pooled. Data and samples acquired from study participants will enable the development of a comprehensive Parkinson's database and biorepository, which will be available to the scientific community to conduct research on novel PD biomarkers.

Conditions

• Parkinson's Disease

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-03-01
• Completion: 2015-03-01
• First posted: 2012-10-12
• Last updated: 2015-10-05

Locations

7 sites across 1 country: United States