NCT01705314

A Randomized Trial of Vitamin D to Reduce Respiratory Infection

Effect of Vitamin D3 Supplementation to Reduce Respiratory Infections in Children and Adolescents in Vietnam: A Blinded, Placebo-controlled Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,300 (actual)
• Sponsor: McMaster University · Academic / Other
• Sex: All
• Age: 3 Years – 17 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to assess the effectiveness of vitamin D in reducing laboratory-confirmed influenza and in reducing non-influenza viral respiratory tract infections. A cohort of children between the ages of 3 and 17 years from the Thanh Ha Commune, Thanh Liem District, Ha Nam Province, Vietnam will be randomized to either weekly vitamin D supplements or placebo. Participants who develop acute respiratory infection over a 12-month period, will be tested for influenza, the co-primary outcome, and other respiratory viruses, the other co-primary outcome, by RT-PCR.

Conditions

• Respiratory Infection

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	vitamin D supplements	Participants will receive 7mls of D-drops (14,000U/week of vitamin D)
DIETARY_SUPPLEMENT	placebo	7mls of placebo drops per week for 8 months.

Timeline

• Start date: 2014-12-01
• Primary completion: 2016-05-01
• Completion: 2016-05-01
• First posted: 2012-10-12
• Last updated: 2016-10-26

Locations

1 site across 1 country: Vietnam