NCT01704612

Evaluation of Block Duration in Type 2 Diabetes Patients

Comparison of Subgluteal Sciatic Nerve Block Duration in Type-2 Diabetic and Non Diabetic Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Pierre and Marie Curie University · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after peripheral nerve block. The investigators hypothesized that block recovery is delayed in diabetic patients.

Detailed description

For diabetic patients, peripheral nerve block is an interesting alternative to general anesthesia because it provides effective analgesia and may decrease haemodynamic complication. The fear of nerve injury after regional anaesthesia in diabetic patients is a concern that has neither been confirmed nor refuted by current literature. As a matter of fact, diabetic patients with neuropathy may be considered at increased risk because of the possibility for double crush syndrome when a chronic axon lesion related to diabetes is associated with an unexpected distal nerve injury related to regional anaesthesia.

Conditions

• Diabetes Type 2

Interventions

Type	Name	Description
DRUG	ropivacaine	patients received 20 mL ropivacaine 5 mg/mL on subgluteal nerve

Timeline

• Start date: 2011-07-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2012-10-11
• Last updated: 2012-12-24

Locations

1 site across 1 country: France