NCT01702025

Rapid Acclimatization to Hypoxia at Altitude

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Colorado State University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

In low oxygen environments, such as altitude, some adults may become ill and suffer from acute mountain sickness. Further, all adults will find that exercising becomes much more difficult when compared with exercise at lower altitudes (e.g. sea-level). The purpose of this investigation is to study the effects of two drugs that may help people adjust to high-altitude quickly, prevent them from becoming ill and improve their exercise performance. The drugs are Methazolamide and Aminophylline.

Conditions

• Physiological Function in Low Oxygen Environment

Interventions

Type	Name	Description
DRUG	Placebo	Yellow corn meal in gel capsules
DRUG	Aminophylline	National Drug Code (NDC) 0143-1020-01
DRUG	Methazolamide	NDC 0781-1072-01
DRUG	Aminophylline+Methazolamide	NDC 0143-1020-01 and NDC 0781-1072-01

Timeline

• Start date: 2012-06-01
• Primary completion: 2012-12-01
• Completion: 2012-12-01
• First posted: 2012-10-05
• Last updated: 2014-10-24
• Results posted: 2014-10-24

Locations

1 site across 1 country: United States