NCT01697098

Dexamethasone for Preterm Labour

Dexamethasone Dosing Interval: 12 or 24 Hours Apart? A Randomized,Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: Female
• Age: 20 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

The investigators sought to determine whether the incidence of neonatal respiratory distress syndrome (RDS) in preterm fetuses is similar with 12- vs 24-hour dosing interval of dexamethasone.

Detailed description

The administration of glucocorticoids to accelerate fetal lung maturity in patients with preterm delivery plays an important role for obstetrics and neonatal care. Many studies have shown that maternal administration of glucocorticoids has a significant beneficial effect in decreasing the incidence of respiratory distress syndrome (RDS) in infants delivered at 28-34 weeks of gestation.

Conditions

• Prematurity

Interventions

Type	Name	Description
DRUG	Dexamethasone 24 hours
DRUG	Dexamethasone 12

Timeline

• Start date: 2012-01-01
• Primary completion: 2012-07-01
• Completion: 2012-08-01
• First posted: 2012-10-02
• Last updated: 2012-10-02

Locations

1 site across 1 country: Egypt