NCT01695304

Trial of Ceramic Water Filters to Reduce Cryptosporidium Infection in Kenya

Pilot Intervention Trial of Ceramic Water Filters to Reduce the Burden of Cryptosporidium in Household Drinking Water in Rural Kenya.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 227 (actual)
• Sponsor: Centers for Disease Control and Prevention · Federal
• Sex: All
• Age: 4 Months – 10 Months
• Healthy volunteers: Accepted

Summary

The aim of the study is to examine the efficacy of ceramic water filters to reduce the burden of waterborne diarrheal illness among infants in selected villages in Kenya. In Kenya very young children are given drinking water or water is used in reconstitution of their food. We hypothesize that ceramic water filters will remove Cryptosporidium from drinking water reducing infection in infants.

Detailed description

Diarrhea is a major cause of illness among children in Africa. Cryptosporidium is a protozoan waterborne diarrheal pathogen resistant to chlorine. Ceramic filters are effective at improving drinking water quality, including removal of protozoa. In a recent preliminary analysis of \>22,000 children \<5 years enrolled in the Global Enterics Multi-Center Study (GEMS) case-control study of moderate-to-severe diarrhea, Cryptosporidium was identified as a leading cause of diarrhea in infants across all four participating African sites. This pilot is the first Cryptosporidium specific intervention trial of household ceramic water filters to reduce the burden of cryptosporidiosis acquired through drinking water in rural Kenya.

Conditions

• Cryptosporidium; Diarrhea
• Cryptosporidiosis
• Communicable Diseases
• Diarrheal Disease

Interventions

Type	Name	Description
OTHER	Ceramic water filter	In total, 120 households with a child 4-10 months old will receive a Cera Maji ceramic water filter for treatment of drinking water at initial entry into the study (intervention group), and 120 households with a child 4-10 months old at initial entry into the study will not receive a ceramic water filter (control group). The study duration will be 6 months. All households in the control group will receive a Cera Maji ceramic water filter when the study ends.

Timeline

• Start date: 2013-01-01
• Primary completion: 2013-08-01
• Completion: 2014-06-01
• First posted: 2012-09-27
• Last updated: 2017-03-22
• Results posted: 2017-03-22

Locations

1 site across 1 country: Kenya