Trials / Completed
CompletedNCT01694615
Cryoprobe Transbronchial Lung Biopsy in Lung Transplant Patients
Prospective Controlled Study of Transbronchial Cryoprobe Versus Forceps Biopsy for Acute Rejection in Lung Transplantation
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Johns Hopkins University · Academic / Other
- Sex
- All
- Age
- 18 Years – 99 Years
- Healthy volunteers
- Not accepted
Summary
Lung transplant recipients undergo bronchoscopy with biopsies for clinical indications and for surveillance in the diagnosis of acute rejection using standard transbronchial forceps. It is recognized that standard forceps biopsies underestimate the presence or degree of airway rejection due to crush artifact and sample size. Transbronchial cryobiopsies have been shown in the literature to provide larger samples without crush artifact in a safe fashion in lung cancer patients. The aim of this study is to determine if transbronchial cryobiopsy is superior to standard transbronchial forceps biopsies in regards to sample size, architecture and the diagnosis of early rejection in lung transplant recipients which if discovered earlier may improve survival.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Cryoprobe biopsy | |
| PROCEDURE | Forceps Biopsy |
Timeline
- Start date
- 2011-11-01
- Primary completion
- 2015-09-01
- Completion
- 2015-09-01
- First posted
- 2012-09-27
- Last updated
- 2016-10-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01694615. Inclusion in this directory is not an endorsement.