Clinical Trials Directory

Trials / Completed

CompletedNCT01694186

Safety and Efficacy of an Injectable Fluocinolone Acetonide Intravitreal Insert

A Phase III, Multi-National, Multi-Center, Randomized, Masked, Controlled, Safety and Efficacy Study of a Fluocinolone Acetonide Intravitreal Insert in Subjects With Chronic Non-Infectious Uveitis Affecting the Posterior Segment of the Eye

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
129 (actual)
Sponsor
EyePoint Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

A study to evaluate the safety and efficacy of an FAI insert for the management of subjects with non-infectious uveitis affecting the posterior segment of the eye.

Detailed description

This is a phase 3, multi-national, multi-center, randomized, masked, controlled study to evaluate the safety and efficacy of an injectable fluocinolone acetonide intravitreal (FAI) insert for the management of subjects with non-infectious uveitis affecting the posterior segment of the eye. Patients will be randomized to receive either a sham injection or the FAI insert and will be observed for three years following treatment.

Conditions

Interventions

TypeNameDescription
DRUGFAI insert
DRUGSham injection

Timeline

Start date
2013-08-02
Primary completion
2018-03-26
Completion
2018-03-26
First posted
2012-09-27
Last updated
2021-04-02
Results posted
2020-03-23

Locations

34 sites across 6 countries: United States, Germany, Hungary, India, Israel, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT01694186. Inclusion in this directory is not an endorsement.