Clinical Trials Directory

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UnknownNCT01693042

Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Mortality in Patients With Chronic Post-infarction Heart Failure

Randomized Controlled Trial to Compare the Effects of Single Versus Repeated Intracoronary Application of Autologous Bone Marrow-derived Mononuclear Cells on Total and SHFM-predicted Mortality in Patients With Chronic Post-infarction Heart Failure

Status
Unknown
Phase
Phase 2 / Phase 3
Study type
Interventional
Enrollment
81 (actual)
Sponsor
Johann Wolfgang Goethe University Hospital · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Single or repeated application of autologous bone marrow-derived stem cells to treat chronic post-infarction heart failure

Detailed description

Improve mortality and morbidity in patients with symptomatic chronic post-infarction heart failure under full dose conventional medical and device treatment including resynchronization therapy, by single versus repeated intracoronary infusion of autologous bone marrow-derived mononuclear cells.

Conditions

Interventions

TypeNameDescription
BIOLOGICALintracoronary infusion of autologous bone marrow-derived cellsIntracoronary infusion into open vessel / bypass supplying previous (\> 3 months) infarct area

Timeline

Start date
2013-11-01
Primary completion
2022-11-01
Completion
2025-01-01
First posted
2012-09-26
Last updated
2020-02-26

Locations

6 sites across 1 country: Germany

Source: ClinicalTrials.gov record NCT01693042. Inclusion in this directory is not an endorsement.