NCT01692015

Diet and Hereditary Haemorrhagic Telangiectasia

A Questionnaire Study on Diet and Hereditary Haemorrhagic Telangiectasia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Hereditary Haemorrhagic Telangiectasia (HHT) affects 1 in 5,000 people. The purpose of this study is to provide data regarding the diet and nosebleed frequency using a questionnaire. This will be filled in by people with HHT. The questionnaire has been designed in paper format.

Detailed description

Hereditary Haemorrhagic Telangiectasia (HHT) affects 1 in 5,000 people, usually causing nosebleeds, skin blood spots, and/or anaemia as a result of bleeding from the nose or gut. The majority of people with HHT also have abnormal blood vessels (arteriovenous malformations) in internal organs such as the lungs, liver and brain. Management of this multisystem disorder is highly challenging. The Lead Applicant has spent 20 years working on this rare disease, and identified multiple areas where more evidence is required to assist clinicians and patients with this lifelong condition. A particular issue is whether the diet influences HHT or its complications in any way. In this study, people will fill in two questionnaires, one giving details of their diet, and another details of their nosebleeds. They will also be asked to consider participating in an accessory study arm which includes weighing food for one week and providing a food diary, in addition to having a single set of blood test.

Conditions

• Hereditary Haemorrhagic Telangiectasia (HHT)

Interventions

Type	Name	Description
OTHER	Questionnaire on dietary history
OTHER	Questionnaire on nosebleed severity
OTHER	One week food diary generated by weighing foods
PROCEDURE	Blood tests for full blood count, albumin, and indices of nutritional status

Timeline

• Start date: 2011-04-01
• Primary completion: 2013-09-01
• Completion: 2016-09-01
• First posted: 2012-09-25
• Last updated: 2024-03-29
• Results posted: 2024-03-29

Locations

1 site across 1 country: United Kingdom