Trials / Completed
CompletedNCT01691001
Effect of Dexmedetomidine on Sevoflurane Requirements and Emergence Agitation in Children Undergoing Ambulatory Surgery
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Yonsei University · Academic / Other
- Sex
- Male
- Age
- 1 Year – 5 Years
- Healthy volunteers
- Not accepted
Summary
Although the aetiology of emergence agitation (EA) derives from multiple factors, it is a frequent side effect of sevoflurane anaesthesia in children. Dexmedetomidine, a potent selective α2-adrenergic agonist, can reduce the doses of hypnotics, opioids, analgesics, and anaesthetics that must be concomitantly administered. This study was conducted to assess the effect of dexmedetomidine infusion on sevoflurane requirements and recovery profiles with EA in children undergoing ambulatory surgery.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Dexmedetomidine | dexmedetomidine(vs saline) 1 mcg/kg iv bolus during 10minutes, and then, 0.1 mcg/kg/h dexmedetomidine(vs saline) was infused. |
| DRUG | normal saline |
Timeline
- Start date
- 2011-08-01
- Primary completion
- 2012-03-01
- Completion
- 2012-03-01
- First posted
- 2012-09-24
- Last updated
- 2012-09-24
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT01691001. Inclusion in this directory is not an endorsement.