NCT01690780

Oral Morphine Versus Ibuprofen

Oral Morphine Versus Ibuprofen for Post-fracture Pain Management in Children: a Randomized Controlled Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 183 (actual)
• Sponsor: Naveen Poonai · Academic / Other
• Sex: All
• Age: 5 Years – 17 Years
• Healthy volunteers: Accepted

Summary

Children 5-17 years of age who have sustained a non-operative distal forearm (radius and/or ulna) or clavicular fracture will be randomized to receive either ibuprofen or oral morphine as needed for pain relief for the first 24 hours following discharge from the emergency department. Pain will be assessed using the self-report Faces pain scale revised (FPS-R). We hypothesize that oral morphine will result in greater pain relief than ibuprofen.

Conditions

• Upper Extremity Fractures
• Analgesia Post Fracture

Interventions

Type	Name	Description
DRUG	Oral morphine	oral morphine 0.5 mg/kg (max 10 mg) every 6 hours as needed for 24 hours
DRUG	Ibuprofen	Ibuprofen 10 mg/kg (max 600 mg) every 6 hours as needed for pain (maximum 4 doses) for 24 hours following discharge from the emergency department

Timeline

• Start date: 2012-09-01
• Primary completion: 2014-02-01
• Completion: 2014-02-01
• First posted: 2012-09-24
• Last updated: 2014-07-16

Locations

1 site across 1 country: Canada