Clinical Trials Directory

Trials / Completed

CompletedNCT01689246

Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease

Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, 15-Month Trial of TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
891 (actual)
Sponsor
TauRx Therapeutics Ltd · Industry
Sex
All
Age
89 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the safety and efficacy of TRx0237 in the treatment of subjects with mild to moderate Alzheimer's Disease.

Conditions

Interventions

TypeNameDescription
DRUGTRx0237 150 mg/dayTRx0237 75 mg tablets will be administered twice daily.
DRUGTRx0237 250 mg/dayTRx0237 125 mg tablets will be administered twice daily.
DRUGPlaceboPlacebo tablets will be administered twice daily. The active placebo tablets include 4 mg of TRx0237 as a urinary and fecal colorant to maintain blinding; hence the placebo group will receive a total of 8 mg/day of TRx0237.

Timeline

Start date
2013-01-01
Primary completion
2015-11-01
Completion
2015-11-01
First posted
2012-09-21
Last updated
2018-03-14

Locations

121 sites across 16 countries: United States, Australia, Bulgaria, Canada, Croatia, Germany, Italy, Malaysia, Poland, Romania, Russia, Singapore, South Korea, Spain, Taiwan, United Kingdom

Source: ClinicalTrials.gov record NCT01689246. Inclusion in this directory is not an endorsement.