NCT01687894

Vasopressin to Prevent Hypotension During Beach Chair Surgery

Clinical Trials of Vasopressin for Prevention of Hypotension During Shoulder Surgery in Beach Chair Position Under General Anesthesia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 74 (actual)
• Sponsor: Chonnam National University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Patients undergoing surgery in beach chair position (BCP) are at risk for cerebral ischaemia. The impacts of arginine vasopressin (AVP) on haemodynamics and cerebral oxygenation are evaluated during surgery in BCP.

Detailed description

Patients undergoing shoulder surgery in BCP under general anaesthesia are randomly allocated to receive i.v. normal saline (control group) or AVP 0.05 or 0.07 U kg-1 (AVP group, n = 15 each) 2 min before moving into BCP. Mean arterial pressure (MAP), heart rate (HR), jugular venous bulb oxygen saturation (SjvO2) and regional cerebral tissue oxygen saturation (SctO2) are measured before (pre-sitting in supine position) and after patients assumed BCP.

Conditions

• Rotator Cuff Tear Arthropathy

Interventions

Type	Name	Description
DRUG	Vasopressins	Vasopressins propofol vasopressins sevoflurane
DRUG	Placebo	Placebo propofol \& placebo sevoflurane
DRUG	propofol	vasopressin propofol \& placebo propofol
DRUG	sevoflurane	vasopressins sevoflurane placebo sevoflurane

Timeline

• Start date: 2012-05-01
• Primary completion: 2014-04-01
• Completion: 2014-12-01
• First posted: 2012-09-19
• Last updated: 2017-02-27

Locations

1 site across 1 country: South Korea