NCT01686022

Grass Sensitisation and Allergic Rhinitis in Thai Patients

The Study of Allergens From Grass and Weed Which Are Causes of Allergic Rhinitis in Thai Patients

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 40 (actual)
• Sponsor: Mahidol University · Academic / Other
• Sex: All
• Age: 10 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Allergic rhinitis patients are the patients who have nasal symptoms when triggered by indoor or outdoor allergens. Outdoor allergen can be divided into grass, tree, or weed. The type of grass or weed are different in various part of the world. The allergens from grass and weed has never been studied in Thailand. This study will find the major allergen from Bermuda grass, Johnson grass, Para grass, sedge, and ragweed, which are very common in Thailand. In addition, the investigators will study about the cross-reactivity among these group of allergen.

Detailed description

To find the major allergen of grass and weed, the serum of patients will be used to bind with the allergen extract by immunoblot study. The ELISA-inhibition will be used to study about cross-reactivity among various kinds of grass and weed.

Conditions

• Allergy to Grass Pollen
• Allergic Rhinitis Due to Weed Pollens

Interventions

Type	Name	Description
OTHER	Immunoblot	serum specific IgE binds to grass extract by immunoblot

Timeline

• Start date: 2012-10-01
• Primary completion: 2015-10-01
• Completion: 2015-10-01
• First posted: 2012-09-17
• Last updated: 2016-09-14

Locations

1 site across 1 country: Thailand