Clinical Trials Directory

Trials / Terminated

TerminatedNCT01685255

A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC or FTC Following Complete Remission With First-line Chemotherapy

A Randomized, Open-Label, Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-Recurrent-Only Epithelial Ovarian Cancer, Primary Peritoneal Carcinoma, or Fallopian Tube Cancer Following Complete Remission With First-Line Chemotherapy

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
83 (actual)
Sponsor
Incyte Corporation · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

This is an open-label, randomized, phase 2 study of an IDO inhibitor, INCB024360 (epacadostat) versus tamoxifen in biochemical recurrent only ovarian cancer patients following complete remission with first-line chemotherapy.

Conditions

Interventions

TypeNameDescription
DRUGEpacadostat
DRUGtamoxifen

Timeline

Start date
2012-08-01
Primary completion
2014-10-23
Completion
2014-10-23
First posted
2012-09-14
Last updated
2019-03-11

Locations

49 sites across 6 countries: United States, Australia, Canada, Russia, Ukraine, United Kingdom

Source: ClinicalTrials.gov record NCT01685255. Inclusion in this directory is not an endorsement.

A Phase 2 Study of the IDO Inhibitor Epacadostat Versus Tamoxifen for Subjects With Biochemical-recurrent-only EOC, PPC (NCT01685255) · Clinical Trials Directory