NCT01684384

Research to Evaluate a Possible Relation Between Values Obtained After Processing CT Images, Lung Function Tests and the Experience of the Patient During an Exacerbation in COPD Patients.

Correlation of Functional Respiratory Imaging Parameters With Lung Function Parameters and Patient Reported Outcome Measures During Exacerbation of COPD.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 53 (actual)
• Sponsor: FLUIDDA nv · Industry
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

In this study the consequences of exacerbations will be visualized by high resolution computed tomography (HRCT) scan at functional residual capacity (FRC) and total lung capacity (TLC) as taken during an episode of exacerbation and after recovering. Changes in HRCT based airway dimensions and computational fluid dynamic (CFD) -based resistance values will be correlated with changes in patient reported outcomes (PROs) and lung function tests recorded at the same time.

Conditions

• Pulmonary Disease, Chronic Obstructive

Interventions

Type	Name	Description
RADIATION	Functional Respiratory Imaging	HRCT scan at FRC and TLC as taken during an episode of exacerbation and after recovering.

Timeline

• Start date: 2012-09-01
• Primary completion: 2014-09-01
• Completion: 2014-09-01
• First posted: 2012-09-13
• Last updated: 2014-12-02

Locations

4 sites across 3 countries: Belgium, Italy, Netherlands