NCT01684280

Obesity-related Genes in Taiwanese Undergoing Weight Loss

Searching for the Most Influential Obesity-related Diabetic Genes and Exploring the Expression Profiles of Those Genes in Taiwanese Undergoing Weight Loss

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Sung Ling Yeh · Academic / Other
• Sex: All
• Age: 19 Years – 63 Years
• Healthy volunteers: Not accepted

Summary

To investigate: 1. Associations between miRNA and insulin signaling-related gene expressions in abdominal adipose tissues in obese subjects. 2. Differences in miRNAs expressed by intrabdominal omental adipose tissues between genders.

Detailed description

Compared the differences in microRNA expressions of abdominal adipose tissue in morbid obese male and female subjects to elucidate the possible regulatory role of microRNA in insulin signaling-related gene expression levels and its association with biochemical markers. We hope to find a miRNA that can be used to predict the syndrome associated with obesity.

Conditions

• Morbid Obesity

Interventions

Type	Name	Description
GENETIC	gender	Paired samples of abdominal subcutaneous and intrabdominal omental adipose tissue were obtained from men and women who underwent bariatric surgery.

Timeline

• Start date: 2010-06-01
• Primary completion: 2010-09-01
• Completion: 2010-09-01
• First posted: 2012-09-12
• Last updated: 2012-09-13

Locations

1 site across 1 country: Taiwan