NCT01683578

Protective Variable Ventilation for Open Abdominal Surgery

Effects of Variable Tidal Volumes During Open Abdominal Surgery on Lung Function and Systemic Inflammation

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Technische Universität Dresden · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

Variable ventilation has been shown to improve lung function and reduce lung damage as well as inflammation in different models of the acute respiratory distress syndrome. Also, variable ventilation is able to recruit lungs. The present study will investigate whether variable as compared to non-variable ventilation improves post-operative lung function and reduces systemic inflammation in patients submitted to open abdominal surgery.

Conditions

• Development of Pulmonary Dysfunction Following Open Abdominal Surgery

Interventions

Type	Name	Description
OTHER	Variable Ventilation

Timeline

• Start date: 2012-09-01
• Primary completion: 2013-09-01
• Completion: 2013-09-01
• First posted: 2012-09-12
• Last updated: 2016-03-31

Locations

1 site across 1 country: Germany