Trials / Withdrawn
WithdrawnNCT01682421
Topical Steroid Treatment After Posterior Lamellar Corneal Transplantation
Investigation of Treatment With Topical Corticosteroid After Posterior Lamellar Corneal Transplantation
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Aarhus University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
After corneal transplantation, topical corticosteroids are used to reduce the risk of rejection. However, the optimal postoperative treatment regimen is unknown. In most cases, a topical steroid is administered for at least 6 months after surgery, but it remains to be determined whether potent steroids offer better protection than weak steroids. Also, the length of the treatment is debated. Since the use of steroids is not without potential serious ocular side effects, it is of considerable importance to investigate these problems. The study aims to examine the frequency of rejection episodes after posterior lamellar keratoplasty; specifically comparing a short course of potent steroids versus a long course of weak steroids.
Conditions
- Endothelial Dystrophy
- Secondary Bullous Keratopathy
- Posterior Lamellar Keratoplasty
- Descemet's Stripping Endothelial Keratoplasty
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Weak steroid (Flurolon, Allergan) | |
| DRUG | Potent steroid (Maxidex, Alcon) |
Timeline
- Start date
- 2012-09-01
- Primary completion
- 2012-09-01
- First posted
- 2012-09-11
- Last updated
- 2014-05-02
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT01682421. Inclusion in this directory is not an endorsement.