NCT01681758

An Assessment of Pulse Pressure Variation to Guide Fluid Therapy in Cardiac Surgery Patients

A Before-and-after Assessment of Pulse Pressure Variation Guided Fluid Therapy in Cardiac Surgery Patients Receiving Mandatory Mechanical Ventilation

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 104 (actual)
• Sponsor: Austin Health · Other Government
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

We aim to test the hypothesis that fluid therapy based on pulse pressure variation (PPV) in patients after cardiac surgery who are mechanically ventilated leads to a significant decrease in the amount of fluid given to such patients in the first 24 hours after surgery

Detailed description

1. The investigators will study patients after cardiac surgery 2. The investigators will collect data on standard care in pre-intervention population 3. The investigators will collect demographic and clinical data 4. The investigators will collect biochemical data in the first 24 hours after surgery 5. The investigators will collect biochemical, physiological and clinical outcome data 6. The investigators will compare the standard care and intervention period data

Conditions

• Cardiac Surgery

Interventions

Type	Name	Description
OTHER	IV fluid according to PPV	intravenous fluids
OTHER	fluids according to standard care

Timeline

• Start date: 2012-01-01
• Primary completion: 2013-04-01
• Completion: 2013-04-01
• First posted: 2012-09-10
• Last updated: 2013-07-11

Locations

1 site across 1 country: Australia