NCT01677208

Danhong Injection in the Treatment of Acute Ischemic Stroke

A Randomized, Multi-center, Double-blind, Placebo-controlled Trial of Danhong Injection in the Treatment of Acute Ischemic Stroke

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,503 (actual)
• Sponsor: China Academy of Chinese Medical Sciences · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether Danhong injection is effective in the treatment of acute ischemic stroke.

Conditions

• Acute Stroke

Interventions

Type	Name	Description
DRUG	Danhong injection	A kind of injection made from two kind of Chinese herbs: Salvia miltiorrhiza and Safflower. 40ml Danhong injection added into 250ml 0.9% saline by an independent research nurse, sealed with brown bag in order to make the investigators and patients blinded, using brown infusion tube for infusion
PROCEDURE	Standard medical care	Standard medical care is in accordance with China Guideline for the diagnosis and treatment of acute ischemic stroke (2010), including medical care for vital signs, control of temperature, blood pressure and glucose, improving cerebral blood circulation, antiplatelet treatment and nutritional supportive care.
DRUG	placebo	0.9% saline added into 250ml 0.9% saline by an independent research nurse, sealed with brown bag in order to make the investigators and patients blinded, using brown infusion tube for infusion.

Timeline

• Start date: 2013-03-13
• Primary completion: 2019-03-10
• Completion: 2019-03-27
• First posted: 2012-08-31
• Last updated: 2022-06-08

Locations

62 sites across 1 country: China