NCT01676857

Chemokine Mechanisms in Chronic Pelvic Pain

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 147 (actual)
• Sponsor: Northwestern University · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to identify biomarkers that can be utilized in the diagnosis of chronic pelvic pain syndrome in men.

Detailed description

Chronic pelvic pain is the hallmark of patients with chronic pelvic pain syndrome (CPPS), a non-bacterial category of prostatitis that is a significant source of morbidity in American men. The cause of CPPS is unknown and there is a lack of convenient biomarkers for diagnosis of this syndrome. This project will examine the expression of biomarkers in expressed prostatic fluid from adult men with and without a diagnosis of CPPS. Thus our specific aim is to validate the use of the chemokines MCP-1 and MIP-1alpha and mast cell tryptase as biomarkers for CPPS in humans and correlate their levels with CPPS symptoms.

Conditions

• Chronic Prostatitis With Chronic Pelvic Pain Syndrome
• Prostatitis

Timeline

• Start date: 2010-05-01
• Primary completion: 2018-01-31
• Completion: 2019-01-24
• First posted: 2012-08-31
• Last updated: 2019-03-13

Locations

1 site across 1 country: United States