NCT01675986

Comparing the Efficacy of Pregabalin and Hydroxyzine on the Anxiety Score

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 306 (actual)
• Sponsor: Poitiers University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The insertion of long-lasting intravenous device is done under local anesthesia. Currently, in the investigators hospital, no premedication is given to the patients. However, this procedure occurs in a particular emotional context related to the diagnosis of cancer or malign hemopathies. Therefore, administration of a sedative or anxiolytic drugs before the start of the procedure can be questionable. Hydroxyzine is the reference molecule for premedication because of its anxiolytic and anti-histaminic properties A new agent, pregabalin, shares also the same properties The main objective of this study was to compare the efficacy of pregabalin and hydroxyzine on the anxiety score as a premedication during the insertion of long-lasting intravenous device under local anesthesia.

Conditions

• Feeling Anxious

Interventions

Type	Name	Description
DRUG	hydroxyzine	75 mg
DRUG	Pregabalin	150 mg
DRUG	Lactose	4 g

Timeline

• Primary completion: 2014-11-01
• First posted: 2012-08-30
• Last updated: 2016-10-11

Locations

1 site across 1 country: France