NCT01675557

Pharmacokinetic Comparison of Vitamin's D2 and D3 in Stage 5 Chronic Kidney Disease Patients on Chronic Hemodialysis

Pharmacokinetic Comparison of Vitamin's D2 and D3 in Stage 5 Chronic Kidney

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Creighton University · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare the pharmacokinetic 25(OH)D and 1,25(OH)2D responses to a single oral dose of vitamin D2 or vitamin D3 in a group of Stage 5-Chronic Kidney Disease subjects requiring chronic hemodialysis.

Detailed description

This is a randomized, single blind, controlled study. Subjects will be randomly assigned to receive 1) placebo capsules (control group); 2) capsules with ergocalciferol (the vitamin D2 group); or 3) capsules with cholecalciferol (the vitamin D3 group).

Conditions

• Chronic Kidney Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vitamin D3	a single oral dose of vitamin D3
DIETARY_SUPPLEMENT	Vitamin D2	a single oral dose of vitamin D2
DIETARY_SUPPLEMENT	Placebo	a single oral dose of placebo

Timeline

• Start date: 2012-09-01
• Primary completion: 2013-05-01
• Completion: 2013-05-01
• First posted: 2012-08-30
• Last updated: 2015-02-26

Locations

1 site across 1 country: United States