NCT01675414

Understanding Gastrointestinal Conditions in Children With Autism Spectrum Disorder (ASD)

Understanding Gastrointestinal Conditions in Children With ASD

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 131 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 2 Years – 17 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to help us learn if children with Autism Spectrum Disorder (ASD) have gastrointestinal (stomach and intestine) problems more frequently than children without ASD do. The investigators hope to learn if children with ASD and gastrointestinal (GI) disorders have certain Problem Behaviors (PB), such as self-injury and aggression, more than children with ASD but no GI disorders do. The investigators want to learn if the Gastrointestinal Symptoms Questionnaire (GIQ) can help us tell which children with ASD also have gastrointestinal disorders. Hypothesis 1: Children with ASD exhibit high rates of symptomatic GI dysfunction that are not identified by current diagnostic evaluation. Hypothesis 2: Painful or discomfort-causing gastrointestinal dysfunctions contribute to an elevated incidence or severity of PB in an identifiable subpopulation of PB-expressing children. The investigators anticipate that the proposed study will raise the standard of medical care for children with ASD by improving current methods of identifying GI dysfunction and determining whether there is a significant relationship between GI dysfunction and PB in this population.

Conditions

• Gastrointestinal Disorders
• Autism Spectrum Disorders

Interventions

Type	Name	Description
OTHER	evaluation visit by a pediatric gastroenterologist	medical history, physical exam completed by pediatric gastroenterologist

Timeline

• Start date: 2008-09-01
• Primary completion: 2010-06-01
• Completion: 2011-02-01
• First posted: 2012-08-30
• Last updated: 2012-08-30

Locations

1 site across 1 country: United States