Clinical Trials Directory

Trials / Unknown

UnknownNCT01675219

Fluorescence Cystoscopy and Optimized MMC in Recurrent Bladder Cancer (FinnBladder 9)

Treatment of Ta Bladder Cancer in High Risk of Recurrence - Fluorescence Cystoscopy With Optimized Adjuvant Mitomycin-C (FinnBladder 9)

Status
Unknown
Phase
Phase 3
Study type
Interventional
Enrollment
400 (estimated)
Sponsor
Turku University Hospital · Other Government
Sex
All
Age
18 Years – 100 Years
Healthy volunteers
Not accepted

Summary

Bladder cancer (BC), the second most common urological malignancy, is an important public health issue. One of the main challenges in the treatment of bladder cancer if the prevention of recurrences of non-invasive tumors, which is also associated with significant costs. The current study will investigate optimal treatment of patients with bladder cancer with high risk of tumor recurrence but low risk of progression. The main interest is comparison of photodynamic (PDD) bladder tumor resection (TUR-BR)to traditional TUR-BT. Also the efficacy of adjuvant optimized mitomycin-C is compared to patients with no adjuvant treatment.

Conditions

Interventions

TypeNameDescription
PROCEDUREwhite light TUR-BTtraditional transurethral bladder tumor resection
PROCEDUREblue light TUR-BTphotodynamic transurethral bladder tumor resection
DRUGoptimized MMCsix weekly optimized mitomycin-C instillations
DRUGsingle immediate chemotherapy instillationsingle immediate post TUR-BT epirubicin (2mg/ml, total of 100 ml) instillation

Timeline

Start date
2012-12-01
Primary completion
2021-12-01
Completion
2023-08-01
First posted
2012-08-29
Last updated
2023-04-13

Locations

10 sites across 1 country: Finland

Source: ClinicalTrials.gov record NCT01675219. Inclusion in this directory is not an endorsement.