NCT01672632

Fat Cell Size and Overfeeding and Etopic Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

It has been shown that large fat cells are associated with more risks for insulin resistance and more cardiovascular risk factors such as high cholesterol or triglycerides.

Detailed description

This study will look at fat cell size and how it affects fat deposition, insulin resistance and muscle oxidative capacity. A comparison will be made with the differences between participants with larger versus smaller fat cells in insulin resistance and blood levels of lipids. The study will also determine if characteristics of fat cells and muscle can predict the development of weight gain-induced insulin resistance.

Conditions

• Over Eating

Interventions

Type	Name	Description
OTHER	Overfeeding	We overfed 40 young, healthy adults by 40% of their baseline energy requirements for 8 weeks. The diet consisted of 41% carbohydrate, 44% fat, and 15% protein.

Timeline

• Start date: 2008-05-01
• Primary completion: 2012-02-01
• Completion: 2020-12-01
• First posted: 2012-08-27
• Last updated: 2021-05-03

Locations

1 site across 1 country: United States