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CompletedNCT01670240

Adalimumab in the Treatment of Chronic Pouchitis

Adalimumab (Humira) in the Treatment of Chronic Pouchitis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
13 (actual)
Sponsor
Odense University Hospital · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study wants to investigate the efficiency of biological treatment for chronic pouchitis. Chronic pouchitis is inflammation in a reconstruction after removal of the colon, a pouch. It is examined in patients with ulcerative colitis. The primary objective evaluation is to evaluate the clinically effect of biological therapy (adalimumab) in patients with chronic pouchitis. Secondary objective is to evaluate the effect of biological therapy on the endoscopical and histological inflammatory activity. It is a double-blinded randomized placebo controlled study.

Conditions

Interventions

TypeNameDescription
DRUGAdalimumab
DRUGPlacebo

Timeline

Start date
2012-08-01
Primary completion
2015-09-01
Completion
2016-01-01
First posted
2012-08-22
Last updated
2016-01-28

Locations

1 site across 1 country: Denmark

Source: ClinicalTrials.gov record NCT01670240. Inclusion in this directory is not an endorsement.

Adalimumab in the Treatment of Chronic Pouchitis (NCT01670240) · Clinical Trials Directory