NCT01669213

Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension

Effects of Different Kinds, Different Doses of 5-HT3 Receptor Antagonists on Prevention of Hypotension After Spinal Anesthesia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to estimate effects of different kinds, different dose of 5-HT3 receptor antagonists on prevention of hypotension after spinal anesthesia

Conditions

• Hypotension
• Shivering
• Nausea and Vomiting
• Vasopressor

Interventions

Type	Name	Description
DRUG	ramosetron	before 5 minutes spinal anesthesia, injection of ramosetron 0.3 mg
DRUG	ondansetron	before 5 minutes spinal anesthesia, injection of ondansetron 8 mg
DRUG	ondansetron	before 5 minutes spinal anesthesia, injection of ondansetron 4 mg
DRUG	placebo	before 5 minutes spinal anesthesia, injection of normal saline 5 ml

Timeline

• Start date: 2012-08-01
• Primary completion: 2012-12-01
• Completion: 2013-08-01
• First posted: 2012-08-20
• Last updated: 2012-08-20

Locations

1 site across 1 country: South Korea