NCT01668927

Empirical Rescue Therapies of Helicobacter Pylori Infection

Helicobacter Pylori Treatment

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 424 (actual)
• Sponsor: Shanghai Jiao Tong University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The increase of antibiotic resistance to H. pylori causes failure of treatment. Furazolidone, amoxicillin and tetracycline are good candidates for rescue therapy since resistance to these three antimicrobials was rare. It is necessary to assess the efficacy and safety of these four bismuth-containing quadruple regimens with above antibiotics as empirical rescue therapies for H. pylori eradication.

Conditions

• Functional Dyspepsia
• Scarred Peptic Ulcer

Interventions

Type	Name	Description
DRUG	Proton Pump Inhibitor
DRUG	Bismuth
DRUG	Metronidazole
DRUG	Tetracycline
DRUG	Furazolidone
DRUG	Amoxicillin

Timeline

• Start date: 2012-07-01
• Primary completion: 2012-09-01
• Completion: 2012-10-01
• First posted: 2012-08-20
• Last updated: 2013-06-04

Locations

1 site across 1 country: China