Trials / Completed
CompletedNCT01666587
Ischemia Reperfusion: Prostaglandins and Antioxidants
The Role of Prostaglandin and Anti-oxidant Availability on Recovery From Forearm Ischemia-reperfusion Injury in Humans
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 12 (actual)
- Sponsor
- University of Essex · Academic / Other
- Sex
- All
- Age
- 18 Years – 45 Years
- Healthy volunteers
- Accepted
Summary
The purposes of this study are two-fold. The first purpose is to determine the effect of taking vitamins on the recovery of an artery (blood vessel) following an induced temporary injury. The second purpose is to determine whether a specific vasodilator is less abundant after the injury and whether this contributes to increased constriction or after the injury. Finally, does vitamin consumption have an effect on the recovery from the injury if one of the substances in the blood that causes vessels to enlarge (dilate) is stopped?
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Antioxidant | |
| DRUG | Prostaglandin inhibitor (Ibuprophen) |
Timeline
- Start date
- 2012-08-01
- Primary completion
- 2013-04-01
- Completion
- 2013-08-01
- First posted
- 2012-08-16
- Last updated
- 2017-05-12
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT01666587. Inclusion in this directory is not an endorsement.