NCT01665235

Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis

The Correlation Study Between Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: RenJi Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Correlation study about Blood Pressure Variability and the prognosis of ischemic stroke with intracranial artery stenosis

Detailed description

Extracranial atherosclerotic stenosis is the main reason for the European and American white ischemic stroke and transient ischemic attack,while Atherosclerotic intracranial arterial stenosis is an important reason for Asian patients with stroke ,accounting for the 33% to 51% of a etiology ratio.The latest research suggests that varying degrees of blood pressure variability can affect the risk of stroke.This study observe the relationship between blood pressure variability and prognosis of ischemic stroke patients with intracranial arterial stenosis,with cranial magnetic resonance imaging (MRI + DWI),magnetic resonance angiography and Trans-cranial Doppler(TCD) .

Conditions

• Blood Pressure Variability
• Intracranial Artery Stenosis

Interventions

Type	Name	Description
DRUG	Amlodipine	The amlodipine - based antihypertensive treatment group (you can add a diuretic or other )
DRUG	ACEI / ARB	ACEI / ARB -based antihypertensive treatment group ( you can add the B - blockers or other)
DRUG	Aspirin or Clopidogrel	aspirin 100mg / d or Clopidogrel 75mg / d (anti-platelet agents)
DRUG	Atorvastatin	Atorvastatin 10 - 40mg / d ( statin therapy)

Timeline

• Start date: 2012-08-01
• Primary completion: 2014-08-01
• Completion: 2014-08-01
• First posted: 2012-08-15
• Last updated: 2012-08-15

Locations

1 site across 1 country: China