NCT01662258

Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For CAP

Microbiology Testing With the Aim Of Directed Antimicrobial Therapy For Community-Acquired Pneumonia

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective interventional study to assess laboratory testing which will identify the microbial cause of pneumonia. This, in turn, will allow targeted antimicrobial agent selection for patients with community acquired-pneumonia (CAP). Hypothesis: 1) To determine if Targeted strategy is non-inferior to Empiric therapy with respect to outcome endpoints. 2) To assess the use of innovative POC tests allows targeted narrow-spectrum antimicrobial therapy. 3) To determine if Targeted strategy is superior to Empiric therapy in patients with viral pneumonia

Detailed description

The study will be conducted at five academic medical university sites with 7 hospitals. Empiric therapy is defined as selection of antibiotic therapy based on the 2007 ATS-IDSA guidelines in which broad-spectrum antibiotics are recommended, and microbial cause is uncertain

Conditions

• Community-acquired Pneumonia

Interventions

Type	Name	Description
DEVICE	Point-of-Care diagnostic laboratory test	All POC tests are FDA-cleared.

Timeline

• Start date: 2012-10-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2012-08-10
• Last updated: 2016-04-19

Locations

5 sites across 1 country: United States