NCT01654848

Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients

Heparin-induced Thrombocytopenia (HIT II) in Liver Transplant Recipients: a Prospective Multivariate Analysis of Prognostic Factors and Haemostaseological Findings

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 39 (actual)
• Sponsor: CHIR-Net · Network
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

In a prospective observational study the incidence of Heparin-induced Thrombocytopenia (HIT) Type 2 after orthotopic liver transplantation, associated factors, and hemostaseological findings in thrombocytes and anti-body patterns is going to be investigated.

Detailed description

The investigators examined the frequency of anti-PF4/heparin antibodies (IgG/M/A; EIA) and their functional activity (HIPA) in 38 whole organ deceased donor liver transplant recipients. Additionally, demographic, clinical, donor- and recipient-specific parameters and laboratory findings (ALAT, ASAT, cholinesterase) were investigated.

Conditions

• Heparin-induced Thrombocytopenia
• Liver Transplantation

Timeline

• Start date: 2010-01-01
• Primary completion: 2011-08-01
• Completion: 2011-08-01
• First posted: 2012-08-01
• Last updated: 2012-08-01

Locations

1 site across 1 country: Germany