NCT01653145

Positive Energy I Through Overfeeding

Behavioral Response to Short-term (Two-day) Positive Energy Balance Through Overfeeding (ENERGY I)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Pennington Biomedical Research Center · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

The purpose of this trial is to examine the metabolic and behavioral effects of a positive energy balance induced by adding food to the usual level of activity. It is hypothesized that: 1) food intake will not differ significantly after 2 days of positive energy balance induced by a high carbohydrate vs. high fat diet when both diets are low in energy density, and 2) food intake will be higher after a positive energy balance induced by a high fat/high energy dense diet vs. a high fat/low energy dense diet.

Detailed description

The purpose of this trial is to examine the metabolic and behavioral effects of a positive energy balance induced by adding food to the usual level of activity. During this study, we will induce a positive energy balance for two days by increasing food intake to 140% of baseline energy requirements and keeping energy expenditure constant. The following three diets, which vary in dietary fat and energy density (kcal/g), will be used to induce the positive energy balance in a within subjects or cross over design: 1) high fat/high energy density, 2) high fat/low energy density, and 3) high carbohydrate/low energy density. Food intake and activity will be measured for 4 days after each diet to quantify the response to positive energy balance and manipulation of dietary fat and energy density.

Conditions

• Obesity

Interventions

Type	Name	Description
OTHER	Diet A	Dietary
OTHER	Diet B	Dietary
OTHER	Diet C	Dietary

Timeline

• Start date: 2010-07-01
• Primary completion: 2012-01-01
• Completion: 2012-01-01
• First posted: 2012-07-30
• Last updated: 2016-01-18

Locations

1 site across 1 country: United States