NCT01652755

Plasma Cystatin C and Acute Kidney Injury

Use of Cystatin C in Predicting AKI in Patients Undergone Cardiopulmonary Bypass Surgery

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 100 (estimated)
• Sponsor: Jinhua Central Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

To evaluate the utility of plasma cystatin C(pCysC) as a predictive and diagnostic marker of acute kidney injury(AKI) in patients undergone cardiopulmonary bypass surgery.

Detailed description

This is a prospective AKI observational study in patients undergone cardiopulmonary bypass surgery. pCysC and plasma creatine will be measured at entry to ICU.AKI was defined as 50% increase in plasma creatine above baseline.The predictive and diagnostic performance of pCysC will be assessed from area under receiver operator characteristic curve(AUC) and odds ratio(OR).

Conditions

• Acute Kidney Injury

Timeline

• Start date: 2011-04-01
• Primary completion: 2013-05-01
• Completion: 2013-05-01
• First posted: 2012-07-30
• Last updated: 2012-08-06

Locations

1 site across 1 country: China