NCT01652612

Positive End-expiratory Pressure and Alveolar Recruitment for One Lung Ventilation

Effects of Positive End-expiratory Pressure and Alveolar Recruitment on the Oxygenation and Respiratory Mechanics During One-lung Ventilation in the Supine Position

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 99 (actual)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Hypoxia frequently develops during one lung ventilation in the supine position.The objective of this article is to study the impact of preemptive alveolar recruitment and subsequent positive end expiratory pressure on arterial oxygenation and lung mechanics during one lung ventilation in the supine position in patients undergoing thoracic surgery .

Detailed description

outcome measures: respiratory parameters (Paw, Ppla, Compliance, Vd/Vt)and oxygenation parameters (PaO2, shunt fraction, Pa-AO2)

Conditions

• One Lung Ventilation

Interventions

Type	Name	Description
OTHER	PEEP	8 cmH2O PEEP throughout the period of OLV and 2nd TLV

Timeline

• Start date: 2011-08-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2012-07-30
• Last updated: 2013-07-04

Locations

1 site across 1 country: South Korea