NCT01648075

Effect of the Consumption of Probiotics in the Reduction of Incidence of Carious Lesions in Preschool Children

Effect of the Consumption of Probiotics Lactobacilli Enriched Milk in the Reduction of Incidence of Carious Lesions in Preschool Children

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 261 (actual)
• Sponsor: University of Chile · Academic / Other
• Sex: All
• Age: 2 Years – 3 Years
• Healthy volunteers: Not accepted

Summary

Probiotics are microorganisms that when administered in adequate amounts can confer health benefits. In vitro and clinical studies support the idea that lactobacilli have protective effects on oral health. A recent study in which preschoolers consumed milk drinks enriched with Lactobacillus rhamnosus, reported a reduction in caries, as well as additional benefits to children. The aim of this study is to evaluate the effect of daily consumption of milk beverages enriched with Lactobacillus rhamnosus on the incidence of caries in preschool Chilean children.

Detailed description

In this randomized controlled trial, preschool children belonging to Integra Foundation will be invited to participate. After obtaining parent´s informed consent, clinical and microbiological testing of saliva at baseline, 6 m, 12m and 18m will be performed. Differences in prevalence and incidence of caries, dmft and microbial diversity between groups will be assessed.

Conditions

• Caries Reduction
• Caries Prevention

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Experimental: Probiotic enriched milk	Milk will be enriched with lactobacillus rhamnosus for the experimental group.

Timeline

• Start date: 2012-07-01
• Primary completion: 2014-01-01
• Completion: 2014-01-01
• First posted: 2012-07-24
• Last updated: 2014-01-22

Locations

1 site across 1 country: Chile