Trials / Withdrawn
WithdrawnNCT01642095
Studying Biomarkers in Samples From Younger Patients With Kidney Cancer
Focal Adhesion Kinase Expression in Pediatric Renal Tumors
- Status
- Withdrawn
- Phase
- —
- Study type
- Observational
- Enrollment
- 0 (actual)
- Sponsor
- Children's Oncology Group · Network
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
This laboratory study is looking into biomarkers in samples from younger patients with kidney cancer. Studying samples of tissue from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. It may also help doctors find better ways to treat cancer.
Detailed description
PRIMARY OBJECTIVES: I. To determine whether focal adhesion kinase (FAK) is expressed and if FAK is phosphorylated in pediatric renal tumors. OUTLINE: Archived tumor tissue samples are analyzed for FAK expression by immunohistochemistry (IHC). IHC staining is compared in normal renal tissue, Wilms tumor (routine and anaplastic), malignant rhabdoid tumor of the kidney, clear cell sarcoma of the kidney, and mesoblastic nephroma.
Conditions
- Childhood Kidney Neoplasm
- Clear Cell Renal Cell Carcinoma
- Congenital Mesoblastic Nephroma
- Rhabdoid Tumor of the Kidney
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Laboratory Biomarker Analysis | Correlative studies |
Timeline
- Start date
- 2012-08-22
- Primary completion
- 2012-09-01
- First posted
- 2012-07-17
- Last updated
- 2018-08-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT01642095. Inclusion in this directory is not an endorsement.