NCT01641068

Memory and Thinking Skills Workshop to Improve Cognition in Gynecologic and Breast Cancer Survivors With Cognitive Symptoms

Behavioral and Neural Indices of Cognitive Rehabilitation in Women's Cancer: A Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Washington · Academic / Other
• Sex: Female
• Age: 21 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine thinking abilities, mood, and quality of life in cancer survivors before and after an 8-week group-based memory and thinking skills workshop. Research participants will include people treated for cancer in the past. Researchers would like to know if there is a relationship between baseline performance on timed attention and memory tasks before receiving memory and thinking skills workshop designed to improve cognition, and performance on such tasks after the workshop.

Detailed description

PRIMARY OBJECTIVES: I. To objectively assess changes in cognitive performance and quality of life (QOL) pre and post participation in a cognitive rehabilitation intervention in gynecologic and breast cancer survivors who have undergone chemotherapy. II. To measure changes in neural function as measured by functional magnetic resonance imaging (fMRI) blood oxygenation level dependent (BOLD) signal and corresponding behavioral responses while performing cognitive tasks. OUTLINE: Patients are randomized to 1 of 2 treatment arms. ARM I (Skills workshop): Patients participate in a memory and thinking skills workshop once weekly for 7 weeks. Patients complete cognitive tests and questionnaires at pre-baseline (Visit 1), baseline (Visit 2), and 7 weeks (Visit 3). ARM II (Education workshop): Patients participate in education workshop for 7 weeks 1-hour duration group focusing on the brain and cognition. Patients complete cognitive tests and questionnaires at pre-baseline (Visit 1), baseline (Visit 2), and 7 weeks (Visit 3).

Conditions

• Breast Carcinoma
• Cancer Survivor
• Cognitive Side Effects of Cancer Therapy
• Malignant Female Reproductive System Neoplasm

Interventions

Type	Name	Description
OTHER	Cognitive Intervention	Participate in memory and thinking skills workshop
OTHER	Educational Intervention	Participate in workshops focusing on increasing knowledge and education on the brain and cognition
PROCEDURE	Functional Magnetic Resonance Imaging	Undergo functional neuroimaging
OTHER	Memory Intervention	Participate in memory and thinking skills workshop
OTHER	Quality-of-Life Assessment	Ancillary studies
OTHER	Questionnaire Administration	Ancillary studies

Timeline

• Start date: 2012-09-12
• Primary completion: 2018-01-01
• Completion: 2018-01-01
• First posted: 2012-07-16
• Last updated: 2019-11-08

Locations

1 site across 1 country: United States