Clinical Trials Directory

Trials / Completed

CompletedNCT01640808

Study of Peretinoin for Suppressing Recurrence of HCV-positive HCC

NIK-333(Peretinoin) PhaseⅢ Study Investigation of the Efficacy and Safety to Suppress Recurrence of Hepatitis C Virus(HCV)-Positive Hepatocellular Carcinoma(HCC), Multicenter, Randomised, Double-blind, Placebo-controlled, Parallel-group Study

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
616 (actual)
Sponsor
Kowa Company, Ltd. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to verify the superiority of NIK-333 (Peretinoin) to placebo in inhibiting the recurrence of HCV-positive HCC in patients showing complete cure of the disease, with the recurrence-free survival as the primary endpoint, in a multi-center, randomized, double-blind, placebo-controlled, parallel-group comparison study.

Conditions

Interventions

TypeNameDescription
DRUGNIK-333(peretinoin)600mg (8 x 75mg capsules) orally, twice a day
DRUGPlaceboPlacebo (8 x Placebo capsules) orally, twice a day

Timeline

Start date
2012-04-01
Primary completion
2016-10-01
Completion
2016-11-01
First posted
2012-07-16
Last updated
2020-12-02
Results posted
2020-12-02

Locations

66 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT01640808. Inclusion in this directory is not an endorsement.