NCT01638039

Identification of Correlates of Protection Against Shigella and Enterotoxigenic Escherichia Coli Infections

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 330 (estimated)
• Sponsor: Hillel Yaffe Medical Center · Other Government
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to accelerate the development of vaccine candidates against diarrheal diseases caused by Shigella and Enterotoxigenic Escherichia coli (ETEC). We plan to identify cases of laboratory-proven shigellosis and ETEC-associated diarrhea, to study humoral and cellular immune parameters following natural infections with Shigella and ETEC, and to compare the level of pre-existing local, humoral and cellular immune parameters in cases of shigellosis and ETEC-associated diarrhea and in matched controls.

Conditions

• Dysentery

Interventions

Type	Name	Description
OTHER	Laboratory Tests	Stool, blood, urine and saliva samples

Timeline

• Start date: 2012-07-01
• Primary completion: 2016-07-01
• Completion: 2016-07-01
• First posted: 2012-07-11
• Last updated: 2012-07-11

Locations

7 sites across 1 country: Israel