NCT01637129

Transcranial Magnetic Stimulation in Children With Stroke

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 4 (actual)
• Sponsor: Nationwide Children's Hospital · Academic / Other
• Sex: All
• Age: 6 Years – 18 Years
• Healthy volunteers: Not accepted

Summary

This is a pilot study of repetitive transcranial magnetic stimulation (rTMS) to test tolerance and efficacy in children who have hemiparesis from acquired or presumed perinatal stroke.

Detailed description

The investigators will begin to test the hypothesis that rTMS will be tolerated and will result in improved hand strength and mobility when compared with sham stimulation. Aim 1: To determine whether 1 Hz rTMS applied to the hemisphere opposite the infarct (contralesional or healthy hemisphere) is tolerated by children ages 6-18 years who have chronic motor sequelae from a stroke. Aim 2: To determine whether 8 sessions of inhibitory 1 Hz rTMS to the contralesional healthy hemisphere improves grip strength and hand mobility when compared with sham stimulation in controls.

Conditions

• Hemiparesis
• Neonatal Stroke
• Ischemic Stroke
• Hemorrhagic Stroke
• Thrombotic Stroke

Interventions

Type	Name	Description
DEVICE	Transcranial Magnetic Stimulation	Transcranial Magnetic Stimulation, repetitive at 1Hz
DEVICE	Sham Magnetic Stimulation	Sham Magnetic Stimulation

Timeline

• Start date: 2012-05-01
• Primary completion: 2013-08-01
• Completion: 2013-08-01
• First posted: 2012-07-10
• Last updated: 2014-04-01

Locations

2 sites across 1 country: United States