Trials / Completed
CompletedNCT01635270
Phase 2 Study Evaluating Mid-position Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-small Cell Lung Carcinoma
Randomized Phase 2 Study Evaluating the Interest of Mid-position Strategy Versus ITV (Internal Target Volume) Strategy in Radiotherapy Treatment for Patients With a Locally Advanced Non-resected Non-small Cell Lung Carcinoma (NSCLC).
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 54 (actual)
- Sponsor
- Centre Leon Berard · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to establish on the market and to clinically evaluate a new strategy of treatment for patients with locally advanced non-small cell lung cancer using deformable repositioning of 4D imaging.
Conditions
- Non-small Cell Lung Cancer
- Radiation Therapy
- Locally Advanced Disease
- Non-metastatic Disease
- Non-resectable Disease
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | mid-position radiation strategy | The midP strategy defines the target as the time weighted average tumor position (mid-position) plus an additional margin, computed specifically for each patient, that takes into account the tumor motion in each direction. This strategy can help to safely reduce toxicity while preserving treatment efficacy |
| RADIATION | ITV | The ITV strategy is the conventional one. It consists in defining the target as the volume covering the whole tumor motion. |
Timeline
- Start date
- 2012-09-12
- Primary completion
- 2020-08-01
- Completion
- 2020-08-01
- First posted
- 2012-07-09
- Last updated
- 2021-02-05
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT01635270. Inclusion in this directory is not an endorsement.