Clinical Trials Directory

Trials / Completed

CompletedNCT01629758

Safety Study of IL-21/Anti-PD-1 Combination in the Treatment of Solid Tumors

A Phase 1 Dose Escalation Study of BMS-982470 (Recombinant Interleukin-21, rIL-21) in Combination With BMS-936558 (Anti-PD-1) in Subjects With Advanced or Metastatic Solid Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
33 (actual)
Sponsor
Bristol-Myers Squibb · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine whether the combination of the 2 drugs being investigated (IL-21 and anti-PD-1) is safe, and provide preliminary information on the clinical benefits of two different schedules of the combination.

Conditions

Interventions

TypeNameDescription
BIOLOGICALDenenicokin
BIOLOGICALNivolumab

Timeline

Start date
2012-06-01
Primary completion
2014-12-01
Completion
2014-12-01
First posted
2012-06-28
Last updated
2015-03-06

Locations

5 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT01629758. Inclusion in this directory is not an endorsement.