NCT01629550

Prospective Randomized Controlled Multicenter Trial of 4 Antiseptic Strategies for Prevention of Catheter Infection in Intensive Care Unit for Adults Patients

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 2,400 (planned)
• Sponsor: Poitiers University Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Catheter related infection is the third cause of nosocomial infection in ICUs. Most of them are avoidable and can be prevent by improving aseptic practices during catheter insertion and maintenance. Indeed, the main route of catheter contamination for short-term catheters is the insertion site. Consequently, the quality of skin disinfection is the most effective preventive measure to reduce the incidence of these infections. This aim of the present study is to compare four strategies of skin disinfection to determine whether a 2% alcoholic solution of chlorhexidine acts better than 5% alcoholic povidone iodine in reducing catheter infection and to assess whether a detersion phase prior to disinfection reduces catheter colonization as compared with no detersion.

Conditions

• Preventing Catheter Related Infection

Interventions

Type	Name	Description
PROCEDURE	skin disinfection prior catheter insertion

Timeline

• Start date: 2012-10-01
• First posted: 2012-06-27
• Last updated: 2016-10-11

Locations

5 sites across 1 country: France