NCT01629017

Long Term Effects On Recipients of Hematopoietic Stem Cell Transplantation

Longitudinal Evaluation of Recipients of Hematopoietic Stem Cell Transplantation (HSCT)

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 800 (estimated)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This project allows for the systematic collection and analysis of long-term follow-up clinical parameters in children who have received a stem cell transplant. The data collected will assist in determining appropriate intervention and treatment plans for patients enrolled on this study. In addition, future patients may benefit by having the ability to anticipate problems and develop methods of prevention or early intervention.

Detailed description

Primary Objective: Implement long-term follow-up guidelines for children, adolescents and young adults who are survivors of HSCT while establishing a database which captures the survivor's lifetime care. Secondary Objectives: * Collect evidence-based data through a structured framework of periodic physical examination, laboratory and medical tests to monitor late effects in our HSCT survivors. * Establish standards of care for late effects of therapy post HSCT for malignant and non-malignant diagnoses. * Provide early identification and intervention towards recognized problems, as well as consistent education to foster a healthy lifestyle to all survivors. * Collect blood and tissue samples to study immune reconstitution of all immune cell types and learn more about immune reconstitution and its affect on post-HSCT complications and disease free survival.

Conditions

• Blood and Marrow Transplant (BMT)

Timeline

• Start date: 1995-01-01
• Primary completion: 2099-01-01
• Completion: 2099-01-01
• First posted: 2012-06-27
• Last updated: 2025-12-24

Locations

1 site across 1 country: United States